Bayern Munich suffered their first Bundesliga defeat of the season against Hoffenheim just four days after their 7-2 Champions League win at Tottenham.
Sargis Adamyan scored twice for Hoffenheim to secure their first league win and first ever at Allianz Arena.
Robert Lewandowski had briefly levelled for champions Bayern with his 15th goal of the season after seven games.
Niko Kovac’s side stay top but now only on goal difference from Frieburg, RB Leipzig and Bayer Leverkusen.
Second-placed Freiburg drew 2-2 at home to Borussia Dortmund, while Leipzig and Leverkusen played out a 1-1 draw.
Source: BBC Sport