Samuel Chukwueze provided the assist for Villarreal’s second goal in their 3-1 win at Qarabag.
Chukwueze set up Paco Alcacer for his side’s second goal in the 85th minute to put them 2-1 ahead.
The Super Eagles winger was later replaced with four minutes left in the game.
Owusu Kwabena opened scoring for Qarabag in the 78th minute before Yeremi Pino equalised for Villarreal on 80 minutes
Alcacer made the game safe for the visitors when he converted a 95th minute penalty.
It is now two wins from two games for Villarreal who top the group on six points.
Olanrewaju Kayode got on the score sheet but could not prevent Sivasspor from losing 2-1 to visiting Maccabi Tel Aviv, in Group I of the Europa League on Thursday.
Kayode put Sivasspor 1-0 ahead in the 55th minute before Dan Biton (pen. 69th minute) and Dor Peretz (74th minute) scored for Maccabi Tel Aviv.
Kayode who has now scored two goals in his second Europa League appearance this season, was replaced on 75 minutes.
It was Sivasspor’s second defeat in the group and are third with no points so far.
Kevin Akpoguma saw 90 minutes of action and helped Hoffenheim beat Gent 4-1 away in Group L.
It was Hoffenheim’s second win after two rounds of games played which place them top on six points.
Red Star and Slovan Liberec both have one point and are second and third respectively.
And in Group K, Chidera Ejuke featured for CSKA in their 0-0 home draw against Dinamo Zagreb.
Ejuke who was on from the start, was later replaced with 15 minutes left in the encounter.
It is now back-to-back draws for CSKA who are second on two points behind leaders Wolfsberger who have four points.
And finally, AC Milan thrashed Sparta Prague 3-0.